biomem.pharm.hokudai.ac.jp
生体機能化学研究室Email : yigarash@pharm.hokudai.ac.jp.
http://biomem.pharm.hokudai.ac.jp/
Email : yigarash@pharm.hokudai.ac.jp.
http://biomem.pharm.hokudai.ac.jp/
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生体機能化学研究室 | biomem.pharm.hokudai.ac.jp Reviews
https://biomem.pharm.hokudai.ac.jp
Email : yigarash@pharm.hokudai.ac.jp.
biomem.pharm.hokudai.ac.jp
最近の業績
http://biomem.pharm.hokudai.ac.jp/publications.html
Sugimoto M., Shimizu Y., Zhao S., Ukon N., Nishijima K., Wakabayashi M., Yoshioka T., Higashino K., Numata Y., Okuda T., Tamaki N., Hanamatsu H., Igarashi Y., Kuge Y. Characterization of the role of sphingomyelin synthase 2 in glucose metabolism in whole-body and peripheral tissues in mice. BBA - Molecular and Cell Biology of Lipids. Mikami D., Sakai S., Sasaki S., Igarashi Y. Journal of Oleo Science. Yuyama K., Igarashi Y. Physiological and Pathological Roles of Exosomes in the Nervous System. Furukawa ...
E-index
http://biomem.pharm.hokudai.ac.jp/english/index.html
Laboratory of Biomembrane and Biofunctional Chemistry,. Frontier Research Center for Post-genome Science and Technology,. Faculty of Advanced Life Science, Hokkaido University. Graduate School of Life Sciences Home Page. Hokkaido University Home Page.
リンク集
http://biomem.pharm.hokudai.ac.jp/link.html
Proc Natl. Acad. Sci. U. S. A. Mol Cell. Biol. Mol Biol. Cell. J Biol. Chem. Biochim. Biophys. Acta-MOL CELL BIOL L. FEBS J. / Eur. J. Biochem. Biochem. Biophys. Res. Commun. Molecular Biology - Research Tool Sites. DDBJ Homology Search System. Lipid Bank for web. ISI Web of Knowledge.
研究内容
http://biomem.pharm.hokudai.ac.jp/MandF.html
当研究室ではその中でもスフィンゴシン１-リン酸 (S1P)、セラミド１-リン酸 (C1P) の様々な生体機能における役割の解明、細胞内動態の解明を目指して研究を行っている。 S1P 受容体を介した S1P のシグナル伝達. S1P は細胞表面に存在する S1P/Edg ファミリー (S1P. Edg8) と呼ばれる G タンパク質に共役した 7 回膜貫通型受容体に特異的に結合することにより、細胞内の-様々な応答を引き起こす Ca. 動員、DNA 合成誘起、MAP キナーゼの活性化、cAMP 濃度の増減など。 我々の研究室では新規の酵素として、ヒト S1P ホスファターゼ hSPP2、 3 ケトジヒドロスフィンゴシンレダクターゼ FVT-1の同定に成功し、解析を行っている。 Email : yigarash@pharm.hokudai.ac.jp.
生体機能化学研究室
http://biomem.pharm.hokudai.ac.jp/jcbl07/index.html
Email : yigarash@pharm.hokudai.ac.jp.
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Biomembranas
Sexta-feira, 7 de outubro de 2011. Desde a origem da vida os seres vivos necessitaram interagir com o meio que os cercam. Entretanto, o meio ambiente e suas substâncias não poderiam ser incorporadas integralmente. Por isso moléculas úteis passaram a ser absorvidas e mantidas na quantidade exata, enquanto que as pouco necessárias foram excluídas do ciclo de vida dos organismos durante toda a evolução. Muitos modelos foram propostos na tentativa de explicar a morfologia e fisiologia das membranas. Mas,...
