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eQuilibrator: The Biochemical Thermodynamics Calculator

EQuilibrator now does pathways! Glucose ⇌ 2 ethanol 2 CO. 2 NADH ⇌ 2 H. O ⇌ ADP phosphate.

http://equilibrator.weizmann.ac.il/

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eQuilibrator: The Biochemical Thermodynamics Calculator | equilibrator.weizmann.ac.il Reviews
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EQuilibrator now does pathways! Glucose &rlhar; 2 ethanol 2 CO. 2 NADH &rlhar; 2 H. O &rlhar; ADP phosphate.
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1 check it out
2 examples
3 reactions
4 compounds
5 enzymes
6 rubisco
7 o 2 nad
8 glucose
9 enolase
10 atp h
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eQuilibrator: The Biochemical Thermodynamics Calculator | equilibrator.weizmann.ac.il Reviews

https://equilibrator.weizmann.ac.il

EQuilibrator now does pathways! Glucose &rlhar; 2 ethanol 2 CO. 2 NADH &rlhar; 2 H. O &rlhar; ADP phosphate.

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1

eQuilibrator relevant publications

http://equilibrator.weizmann.ac.il/cite

A Flamholz, E. Noor, A. Bar-Even, R. Milo,. EQuilibrator - the biochemical thermodynamics calculator. Nucleic Acids Res (2012) 40:D770-5. E Noor, A. Bar-Even, A. Flamholz, Y. Lubling, D. Davidi, R. Milo,. An integrated open framework for thermodynamics of reactions that combines accuracy and coverage. E Noor, H.S. Haraldsdóttir, R. Milo, R.M.T. Fleming,. Consistent Estimation of Gibbs Energy Using Component Contributions. PLoS Comput Biol (2013) 9:e1003098. DOI: 10.1371/journal.pcbi.1003098].

2

About eQuilibrator

http://equilibrator.weizmann.ac.il/about

EQuilibrator is a simple web interface designed to enable easy thermodynamic analysis of biochemical systems. eQuilibrator enables free-text search for biochemical compounds and reactions and provides thermodynamic estimates for both in a variety of conditions. Estimation of thermodynamic parameters (Δ. G and Δ. G) elucidates how much energy is required to drive a particular biochemical reaction and in which direction the reaction will flow in particular cellular conditions [1-2]. Avi Flamholz, Elad Noor...

3

eQuilibrator FAQ

http://equilibrator.weizmann.ac.il/faq

How do I search for a compound or enzyme? How do I search for a reaction? What are "standard conditions? How do you deal with gases like O. How can I set for standard conditions in reactions involving a gas? What are Δ. G°, Δ. G'° and Δ. What are Δ. G° and Δ. What does the 'm' in Δ. Why is ΔG "not available? How do you calculate the uncertainty for each estimation? Why can't I change the concentration of Hydrogen ions? Why can't I change the concentration of water? Why can't I change the temperature?

4

Download eQuilibrator Data

http://equilibrator.weizmann.ac.il/download

Formats and Data Sources. EQuilibrator data is given in two formats. Tabular data is given as CSV and hierarchical data is given in JSON. JSON: the JavaScript Object Notation. Format is a lightly structured hierarchical format that is easily parsed in most modern programming languages. CSV: Comma-Separated Value format is a flat format that is mostly unstructured, easy to parse and easy to view in Excel and other spreadsheet programs. PH = 5.0 : Download. PH = 5.5 : Download. PH = 6.0 : Download. The sta...

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New in version 2.0

http://equilibrator.weizmann.ac.il/whats_new

What's new in eQuilibrator 2.0? Of each estimation is now provided. For example, when we write Δ. G' = -32.1 ± 1.4. KJ/mol], the 1.4 represents a 95% confidence interval around the estimated Gibbs energy. This change was facilitated by upgrading our software to the more precise Component Contribution method. A dedicated page for reduction potentials. See for example Oxaloacetate reduction. Gas, liquid and solid phase for the relevant compounds (e.g. you can use O. G) in glucose oxidation. New in 2.0.

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EQuilibrator now does pathways! Glucose &rlhar; 2 ethanol 2 CO. 2 NADH &rlhar; 2 H. O &rlhar; ADP phosphate.

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