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KT5823
KT5823 is a semi-synthetic derivative of K525a. It is a potent, selective inhibitor of cGMP-dependent protein kinase (PKG) ( in vitro. 234nM). KT5823 interferes at the level of the ATP binding site of the catalytic domain of PKG. The PKG are Ser/Thr protein kinase with broad substrate specificity, and expressed in; brain, smooth muscle cells, platelets, juxtaglomerular kidney cells, and endothelial cells. Soluble in DMSO and DMF. 1: Mol Hum Reprod. 2003 Dec;9(12):775-83. Related Articles, Links. Departme...
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