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Signum Biosciences

THE PROMISE OF PP2A. Discovering novel therapeutics for the treatment of neurodegenerative disorders. Through research on protein networks that control biological systems, Signum is developing therapeutic agents for Alzheimer’s, Parkinson’s, and other neurodegenerative diseases. Signum Biosciences spin out, Signum Dermalogix, is focused on developing new and innovative dermatological products with a commitment to quality, efficacy and safety. Research and Funding Provided by:.

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THE PROMISE OF PP2A. Discovering novel therapeutics for the treatment of neurodegenerative disorders. Through research on protein networks that control biological systems, Signum is developing therapeutic agents for Alzheimer’s, Parkinson’s, and other neurodegenerative diseases. Signum Biosciences spin out, Signum Dermalogix, is focused on developing new and innovative dermatological products with a commitment to quality, efficacy and safety. Research and Funding Provided by:.

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Signum Biosciences | signumbiosciences.com Reviews

https://signumbiosciences.com

THE PROMISE OF PP2A. Discovering novel therapeutics for the treatment of neurodegenerative disorders. Through research on protein networks that control biological systems, Signum is developing therapeutic agents for Alzheimer’s, Parkinson’s, and other neurodegenerative diseases. Signum Biosciences spin out, Signum Dermalogix, is focused on developing new and innovative dermatological products with a commitment to quality, efficacy and safety. Research and Funding Provided by:.

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signumbiosciences.com

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Partners | Signum Biosciences

http://www.signumbiosciences.com/category/partners

Signum has productive collaborations with a number of leading researchers and institutions to advance our programs and advance the scientific foundation of our platform. Donald C. Lo, Ph. D., Duke University. New York State Institute For Basic Research In Developmental Disabilities. M Maral Mouradian, M.D., Rutgers-Robert Wood Johnson Medical School. M Maral Mouradian, M.D., is the William Dow Lovett Professor of Neurology and Director of the Center of Neurodegenerative and Neuroimmunologic Disea...Signu...

2

News | Signum Biosciences

http://www.signumbiosciences.com/category/news

Signum Biosciences was invited to Saint Louis, Missouri to give a presentation on our isoprenylcysteine (IPC) cosmetic functional ingredients (CFI). 8220;Neuroprotective properties of EHT” presented at the Experimental Biology Conference in San Diego. Signum scientists were invited to Seoul South Korea to speak. Our scientific team was invited to Seoul South Korea to discuss the science behind SIG1273, our 2nd generation isoprenylcysteine (IPC) cosmetic functional ingredient (CFI) and eicosanoyl-5-hydrox...

3

Currently there are no remedies that prevent or halt the progression of these diseases | Signum Biosciences

http://www.signumbiosciences.com/therapeuticmarkets

The Market For Neurodegenerative Therapeutics. Currently there are no remedies that prevent or halt the progression of these diseases. Alzheimer’s Disease (AD), Parkinson’s Disease (PD) and an array of related disorders that are characterized by progressive neuronal loss are a huge and increasing health care problem affecting millions worldwide. The only available therapeutics have limited efficacy and only treat the symptoms. Neurodegenerative disorders are a dire public health problem. Development of d...

4

Spearheading a novel, disease modifying mechanism for neurodegenerative disorders | Signum Biosciences

http://www.signumbiosciences.com/pp2a

Spearheading a novel, disease modifying mechanism for neurodegenerative disorders. Research has largely focused on pathological hallmarks seen at the endpoint of disease, until now. Research and Funding Provided by:. 2016 Signum Biosciences, Inc., The Science of Staying Healthy.

5

Board of Directors | Signum Biosciences

http://www.signumbiosciences.com/boards

Experienced and distinguished experts. Jeffry Stock, PhD CHAIRMAN. Gregory Stock, PhD. Jeffry Stock, PhD CHAIRMAN. Maxwell Stock PRESIDENT and CEO. Gregory Stock, PhD BOARD MEMBER. Stephen Modzelewski BOARD MEMBER. Yoichi Kambara BOARD MEMBER. Jeffrey Cummings, MD. Khalid Iqbal, PhD. Yigong Shi, PhD. Scott Vafai, MD. Jeffrey Cummings, MD BOARD MEMBER. Khalid Iqbal, PhD BOARD MEMBER. Yigong Shi, PhD BOARD MEMBER. Scott Vafai, MD BOARD MEMBER. Research and Funding Provided by:.

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signumdermalogix.com

Pipeline – Signum Dermalogix

http://signumdermalogix.com/pipeline

Developing Dermatology Assets in the Cosmetic and Drug Space. Isoprenylcysteine (IPC) analogs are a novel technology platform with broad utility over multiple inflammatory dermatological conditions. Signum’s approach is to develop small molecules that modulate G-protein-mediated and toll-like receptor-mediated signal transduction to achieve substantial therapeutic relief and/or provide anti-inflammatory and anti-aging protection to the skin. These small molecules inhibit signaling activation in the membr...

signumdermalogix.com

Partners – Signum Dermalogix

http://signumdermalogix.com/partners

Signum Dermalogix, Inc. partners with some of the top skincare and cosmetics companies in the world to bring breakthrough science to the skin of millions. Product. We look forward to collaborating with Elizabeth Arden’s efforts in producing innovative, high quality skin care products supported with robust scientific data. See Our Services Catalog.

signumdermalogix.com

Services – Signum Dermalogix

http://signumdermalogix.com/services

Signum Dermalogix offers innovative testing, analytical and advisory solutions for your cosmetic and/or lead drug candidates. Utilizing our dermatological expertise we can provide safety and activity data to help differentiate your product from competitors. Furthermore, once the requisite data is obtained we can assist medical writing and out-licensing efforts for your product. For additional information and description of the services discussed below please review our Catalog. Determine activity of each...

signumdermalogix.com

News – Signum Dermalogix

http://signumdermalogix.com/category/news

Signum presented two posters at this years Society for Investigative Dermatology (SID) meeting in Scottsdale, Arizona. May 13, 2016. May 12, 2016. Dr Eduardo Perez and Dr. Jose Fernandez, attended this years Society for Investigative Dermatology (SID) to present the research conducted at Signum Dermalogix. They presented two posters this year one titled, “SIG-1191TM: A novel hydrating cosmetic functional ingredient (CFI) for Read More …. Signum scientists were invited to Seoul South Korea to speak. Maxwe...

signumdermalogix.com

About SIG-1273 – Signum Dermalogix

http://signumdermalogix.com/sig1273

Protect against UVA damage. Protect against oxidative stress. Anti-wrinkle (reduces collagenase production, which protects collagen). Protects against chemical induced pro-inflammatory cytokine release. Protects against bacterial induced (TLR2) pro-inflammatory cytokine release. Protects against metal induced (TLR4) induced pro-inflammatory cytokine release. Protects against T-cell induced pro-inflammatory cytokine release. Protects against UV induced pro-inflammatory cytokine release. Anti-inflammatory,...

signumdermalogix.com

About – Signum Dermalogix

http://signumdermalogix.com/about

Signum Dermalogix, a spin out of Signum Biosciences is a private biotech company founded in 2011 from technologies developed by Dr. Jeffry Stock at Princeton University (see Figure below). We develop cosmetic functional ingredients as well as topical drug candidates for dermatological disease. Technology based on the signal transduction work of Dr. Jeffrey Stock at Princeton University (early 90s). Dermalogix spin-out in 2011 of the dermatology assets and service testing. See Our Services Catalog.

signumdermalogix.com

About SIG1322 – Signum Dermalogix

http://signumdermalogix.com/sig1322

There is a need for safe and effective topical therapeutic agents for the treatment of atopic dermatitis (AD), whose prevalence is increasing. SIG1322 is our 2nd isoprenylcysteine (IPC) drug development candidate. Funded primarily through SBIR grants via the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) we are in the preclinical/discovery phase for this molecule. Proposed Mechanism of Action. See Our Services Catalog.

everydayyouth.net

My Experience with EHT - Everyday Youth

http://www.everydayyouth.net/my-experience-with-eht

Nerium International Independent Brand Partner. Nerium AD – Age-Defying Treatment. Nerium Firm – Body Contouring Cream. EHT Age-Defying Brain Supplement. Nerium Age-Defying Day Cream. How to Become a Nerium Brand Partner. Opportunities in Hong Kong. EHT Age-Defying Brain Supplement. My Experience with EHT. June 12, 2015. I was excited when I first heard about Nerium’s partnership with Signum Biosciences. I started reading up on the product and even looked at a few scientific papers on PP2A. Today I woke ...

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Signum Biosciences

THE PROMISE OF PP2A. Discovering novel therapeutics for the treatment of neurodegenerative disorders. Through research on protein networks that control biological systems, Signum is developing therapeutic agents for Alzheimer’s, Parkinson’s, and other neurodegenerative diseases. Signum Biosciences spin out, Signum Dermalogix, is focused on developing new and innovative dermatological products with a commitment to quality, efficacy and safety. Research and Funding Provided by:.

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Biuro aktuarialne – Aktuariusz - Wyceny rezerw pracowniczych

Aktuariusz, usługi aktuarialne. Biuro Usług Aktuarialnych Signum istnieje od 2004 roku. Jesteśmy jednym z najbardziej doświadczonych i uznanych firm zajmujących się doradztwem aktuarialnym. W ofercie biura usługi aktuarialne. Biuro Aktuarialne Signum specjalizuje się w usługach aktuarialnych. To wszechstronny specjalista, zajmujący się szacowaniem ryzyka oraz wartości bieżącej projektów finansowych, w szczególności długoterminowych lub obarczonych ryzykiem. Aktuariusz. Ze szczególnym naciskiem na wycenę ...

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Signumbloggen | Katolsk orientering om kyrka, kultur och samhälle

Katolsk orientering om kyrka, kultur och samhälle. En velpelle till påve i Morettis nya film. I övrigt skildras kardinalerna mest som välmenande och aningen världsfrånvända äldre herrar. Rysk-ortodoxa och katoliker i gemensamt försvar av kristna värden. Ortodoxa och katoliker har bildat en front för att försvara de kristna värdena i det moderna samhället, enligt patriarken. Den gemensamma uppfattningen i flera frågor är mycket viktig för konsolideringen av det ryska samhället . Pezzi nämnde, enli...Att P...

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