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BioPlex

The BioPlex ( b. Network is the result of creating thousands of cell lines with each expressing a tagged version of a protein from the ORFeome collection. Immunopurification of the tagged protein and detection of associated proteins by mass spectrometry are the building blocks of the network. The overarching project goal is to determine protein interactions for every member of the collection. A first paper in Cell. The BioPlex Network: A Systematic Exploration of the Human Interactome.

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BioPlex | wren.hms.harvard.edu Reviews
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The BioPlex ( b. Network is the result of creating thousands of cell lines with each expressing a tagged version of a protein from the ORFeome collection. Immunopurification of the tagged protein and detection of associated proteins by mass spectrometry are the building blocks of the network. The overarching project goal is to determine protein interactions for every member of the collection. A first paper in Cell. The BioPlex Network: A Systematic Exploration of the Human Interactome.
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1 download interactions
2 browse interactions
3 download ms data
4 download comppass
5 people
6 links
7 bioplex
8 iophysical i
9 nteractions of o
10 rfeome based com plexes
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BioPlex | wren.hms.harvard.edu Reviews

https://wren.hms.harvard.edu

The BioPlex ( b. Network is the result of creating thousands of cell lines with each expressing a tagged version of a protein from the ORFeome collection. Immunopurification of the tagged protein and detection of associated proteins by mass spectrometry are the building blocks of the network. The overarching project goal is to determine protein interactions for every member of the collection. A first paper in Cell. The BioPlex Network: A Systematic Exploration of the Human Interactome.

INTERNAL PAGES

wren.hms.harvard.edu wren.hms.harvard.edu
1

BioPlex

http://wren.hms.harvard.edu/bioplex/downloadData.php

Raw data can be retrieved by searching for desired baits via gene ID. Select desired baits and click download to proceed. This tool is intended for limited raw data download. For additional data please contact us.

2

BioPlex

http://wren.hms.harvard.edu/bioplex/index.php

The BioPlex ( b. Network is the result of creating thousands of cell lines with each expressing a tagged version of a protein from the ORFeome collection. Immunopurification of the tagged protein and detection of associated proteins by mass spectrometry are the building blocks of the network. The overarching project goal is to determine protein interactions for every member of the collection. A first paper in Cell. The BioPlex Network: A Systematic Exploration of the Human Interactome.

3

BioPlex

http://wren.hms.harvard.edu/bioplex/bioplexTeam.php

Project Design / Leadership.

4

BioPlex

http://wren.hms.harvard.edu/bioplex/downloadInteractions.php

Download BioPlex protein-protein interaction data. Select a dataset to download and view interactions. BioPlex Interaction List (published). List of interactions through 02/01/2015. Equivalent to Supp. 2 (manuscript in press). BioPlex Interaction List (current). List of interactions through 06/12/2015.

5

BioPlex

http://wren.hms.harvard.edu/bioplex/browseInteractions.php

Please follow the following steps to browse the interaction data. Download and install the freely available CDF player from Wolfram: CDF Player. Download the data and user interface in the notebook format ('.cdf') below. Locate and double click the '.cdf' file. Interaction network browser (may requre up to 30 secs. to load). Full network through 02/01/2015. Bait and prey assignments through 02/01/2015.

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The BioPlex ( b. Network is the result of creating thousands of cell lines with each expressing a tagged version of a protein from the ORFeome collection. Immunopurification of the tagged protein and detection of associated proteins by mass spectrometry are the building blocks of the network. The overarching project goal is to determine protein interactions for every member of the collection. A first paper in Cell. The BioPlex Network: A Systematic Exploration of the Human Interactome.

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