primesdb.org

PrimesDB portal to protein-protein interaction networks: Home

Is a systems biology platform that is being developed to enable the collection, integration and analysis of state-of-the-art genomics, proteomics and mathematical modelling data being generated by the PRIMES project. PRIMES is investigating the role of protein interaction machines in oncogenic signalling with a particular focus on the EGFR network. PRIMESDB. Provides a centralised knowledgebase and analysis platform for cancer protein interaction networks. Bait Proteins (Click to expand). Log in to search.

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Kenneth Bryan

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Kenneth Bryan

Systems Biology/Immunol●●●●●●●●●●●●●●●●●●●●●●●ce Research Department,

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PrimesDB portal to protein-protein interaction networks: Home | primesdb.org Reviews

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Is a systems biology platform that is being developed to enable the collection, integration and analysis of state-of-the-art genomics, proteomics and mathematical modelling data being generated by the PRIMES project. PRIMES is investigating the role of protein interaction machines in oncogenic signalling with a particular focus on the EGFR network. PRIMESDB. Provides a centralised knowledgebase and analysis platform for cancer protein interaction networks. Bait Proteins (Click to expand). Log in to search.

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1 primesdb

2 primes project

3 the team

4 resources

5 egfr overview

6 egfr core network

7 psi mi standards

8 primes ppi data

9 molecules

10 interactions

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PrimesDB portal to protein-protein interaction networks: Home | primesdb.org Reviews

https://primesdb.org

Is a systems biology platform that is being developed to enable the collection, integration and analysis of state-of-the-art genomics, proteomics and mathematical modelling data being generated by the PRIMES project. PRIMES is investigating the role of protein interaction machines in oncogenic signalling with a particular focus on the EGFR network. PRIMESDB. Provides a centralised knowledgebase and analysis platform for cancer protein interaction networks. Bait Proteins (Click to expand). Log in to search.

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primesdb.org

1

PrimesDB portal to protein-protein interaction networks: EgfrOverview

http://www.primesdb.org/pages/egfrOverview

Developed by the Lynn EMBL Australia Group at SAHMRI. The research leading to these results received funding from the European Union Seventh Framework Programme. FP7/2007-2013) PRIMES project under grant agreement number FP7-HEALTH-2011-278568.

2

PrimesDB portal to protein-protein interaction networks: PrimesProject

http://www.primesdb.org/pages/primesProject

PRIMES: Protein interaction machines in oncogenic EGF receptor signalling. PRIMES: Protein interaction machines in oncogenic EGF receptor signalling. PRIMES is a 13 Partner Collaborative European FP7 - HEALTH - 2011 project in the theme "Proteins and their interactions in health and disease". PRIMES investigates the following:. How do protein interactions contribute to the generation of biological specificity in signalling? How do pathogenetic perturbations affect protein interaction networks? Validate t...

3

PrimesDB portal to protein-protein interaction networks: PsiMiStandards

http://www.primesdb.org/pages/psiMiStandards

Proteomics Standards Initiative (PSI). HUPO-PSI defines community standards for data representation in proteomics to facilitate data comparision, exchange and verification. It was founded at the HUPO meeting in Washington, April 28-29, 2002. Molecular Interaction XML Format Documentation. The PSI MI format is a data exchange format for molecular interaction. It is not a proposed database structure. OLS) - Ontology Lookup Service. It is a spin-off of the PRIDE project, which required a centralized query i...

4

PrimesDB portal to protein-protein interaction networks: ResultIndex

http://www.primesdb.org/pages/resultIndex

The pipeline takes each protein in the current EGFR/ERRB core network and queries all PSICQUIC databases for all interactions involving this protein. This network can be downloaded in several formats from here. The PRIMESDB team has integrated the EGFR network information with:. A) Protein structure information from the PDB database (all nodes with at least a partial crystal structure in PDB for the human protein are shown). B) Drug target information from DrugBank. What are the 198 EGFR core proteins?

5

PrimesDB portal to protein-protein interaction networks: Primesdb

http://www.primesdb.org/pages/primesdb

Is a systems biology analysis platform that is being developed to enable the collection, annotation, integration and analysis of proteomics, imaging, structural biology and computational and mathematical modelling data being generated by the PRIMES project. It will provide a "one-stop-shop" for knowledge and analysis of the EGFR/ERBB. Network for both the project collaborators and the wider scientific community. Is being developed by the Lynn EMBL Australia Group at SAHMRI. Linking protein interaction da...

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imexconsortium.org

About IMEx | The International Molecular Exchange Consortium

http://www.imexconsortium.org/about-imex

The International Molecular Exchange Consortium. Consortium is an international collaboration between a group of major public interaction data providers who have agreed to share curation. Develop and work to a single set of curation. Rules when capturing data from both directly deposited interaction data or from publications in peer-reviewed journals. Capture full details of an interaction in a deep curation. Perform a complete curation. Provide the data in standards compliant download formats. Http:/ mi...

imexconsortium.org

Home | The International Molecular Exchange Consortium

http://www.imexconsortium.org/home

The International Molecular Exchange Consortium. Search the IMEx data resource. A non-redundant set of protein-protein interaction data from a broad taxonomic range of organisms. From direct submissions or peer-reviewed journals to a consistent high standard. Available in standard formats MITAB. Or PSI-MI XML 2.5. Provided by a network of participating major public domain databases. Orchard, S., et al. Protein interaction data curation. The International Molecular Exchange ( IMEx. An overview of the IMEx.

imexconsortium.org

Submit Your Data | The International Molecular Exchange Consortium

http://www.imexconsortium.org/submit-your-data

The International Molecular Exchange Consortium. IMEx partner databases request the following minimum information about a molecular interaction experiment to be provided with each data deposition. Data should be MIMIx compatible. Submitters should supply the following information. Host system (NCBI taxid and details of tissue, cell line). Participant to be identified by either molecule identifiers from a public domain database or a sequence accompanied by species of origin (NCBI taxid). IntAct ( www....

imexconsortium.org

Training | The International Molecular Exchange Consortium

http://www.imexconsortium.org/training

The International Molecular Exchange Consortium. Course Title: Networks and Pathways. Nr Cambridge, CB10. Trust Genome Campus, Hinxton. IMEx is funded by the European Commission under PSIMEx, contract number FP7-HEALTH-2007-223411. Site maintained by the External Services team at EMBL-EBI. The International Molecular Exchange Consortium.

imexconsortium.org

Licence | The International Molecular Exchange Consortium

http://www.imexconsortium.org/licence

The International Molecular Exchange Consortium. The International Molecular Interaction Exchange ( IMEx. Is a collaboration between IntAct. DIP, MINT, MPIDB. And Molecular Connections. The IMEx. Consortium applies the Creative Commons Attribution License ( http:/ creativecommons.org/licenses/by/2.5/. This means that you are free to copy, distribute, display and make commercial use of all IMEx. IMEx is funded by the European Commission under PSIMEx, contract number FP7-HEALTH-2007-223411.

imexconsortium.org

Admin | The International Molecular Exchange Consortium

http://www.imexconsortium.org/admin

The International Molecular Exchange Consortium. IMEx is funded by the European Commission under PSIMEx, contract number FP7-HEALTH-2007-223411. Site maintained by the External Services team at EMBL-EBI. The International Molecular Exchange Consortium.

imexconsortium.org

Curation | The International Molecular Exchange Consortium

http://www.imexconsortium.org/curation

The International Molecular Exchange Consortium. Rules are explained in full in the Curation. Manual. Individual databases may locally impose additional rules, but these will be additional to and not break the agreed IMEx. Users may request the curation. Of specific papers not currently included in the IMEx. Data set. One of the IMEx. Databases will then annotate the paper (assuming the data within is of sufficient quality) and release the data as quickly as possible. If you wish to request curation.

imexconsortium.org

Disclaimer | The International Molecular Exchange Consortium

http://www.imexconsortium.org/disclaimer

The International Molecular Exchange Consortium. We make no warranties regarding the correctness of the data, and disclaim liability for damages resulting from its use. We cannot provide unrestricted permission regarding the use of the data, as some data may be covered by patents or other rights. IMEx is funded by the European Commission under PSIMEx, contract number FP7-HEALTH-2007-223411. Site maintained by the External Services team at EMBL-EBI. The International Molecular Exchange Consortium.

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PrimesDB portal to protein-protein interaction networks: Home

Is a systems biology platform that is being developed to enable the collection, integration and analysis of state-of-the-art genomics, proteomics and mathematical modelling data being generated by the PRIMES project. PRIMES is investigating the role of protein interaction machines in oncogenic signalling with a particular focus on the EGFR network. PRIMESDB. Provides a centralised knowledgebase and analysis platform for cancer protein interaction networks. Bait Proteins (Click to expand). Log in to search.

primesdb.org

PrimesDB portal to protein-protein interaction networks: Home

Is a systems biology platform that is being developed to enable the collection, integration and analysis of state-of-the-art genomics, proteomics and mathematical modelling data being generated by the PRIMES project. PRIMES is investigating the role of protein interaction machines in oncogenic signalling with a particular focus on the EGFR network. PRIMESDB. Provides a centralised knowledgebase and analysis platform for cancer protein interaction networks. Bait Proteins (Click to expand). Log in to search.

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